High-Grade Transformation of Acinic Cell Carcinoma: Potentially Underrecognized and Inadequately Treated

High-Grade Transformation (Dedifferentiation) of Acinic Cell Carcinoma of the Parotid Gland: Report of an Unusual Variant

Acinic cell carcinoma with high-grade transformation of the salivary gland is an unusual variant with less than fifty cases being reported in the literature. It is characterized by a low- and high-grade component juxtaposed with one another and tends to take on a more aggressive clinical course than its low-grade counterpart, suggesting a poor clinical outcome. We, hereby, report a case of acin...

Intraosseous acinic cell carcinoma.

Acinic cell carcinoma is an uncommon low-grade malignant tumor of salivary glands. It was first described by Nasse in 1892, arising in parotid salivary gland. Salivary gland tumors are also known to develop within jaw bones, arising within the jaw as a primary central lesion, and are extremely rare with only a few cases reported. We present a rare case report of 65-year-old woman with intraosse...

Salivary gland acinic cell carcinoma.

Primary acinic cell carcinoma of the breast.

Seven cases of this rare variant of breast carcinoma have been described in three previous publications. This paper describes an additional case, the first following chemotherapy, which in addition had an unfavourable prognosis. It also describes alterations in cell morphology, immunohistochemistry, and ultrastructure following chemotherapy.

Pure acinic cell carcinoma of the breast

Rationale:Acinic cell carcinoma (AcCC) of the breast is a rare histological type of malignant epithelial neoplasm exhibiting acinic cell differentiation. Patient concerns: A 52-year-old woman presented to the hospital with a palpable mass over the upper outer quadrant of the right breast. Diagnoses:Physical examination revealed an irregular mass in the lateral upper quadrant of the left breast,...